221Furthermore, the discretion enjoyed by the Commission and the limits which it has placed on that discretion in the Guidelines do not, in principle, prejudge the exercise by the Courts of the Union of their unlimited jurisdiction, which empowers them to annul, increase or reduce the fine imposed by the Commission (see Case T-127/04KME Germany and Others v Commission [2009] ECR II-1167, paragraph 37 and the case-law cited).