22It should be noted that, under the second paragraph of Article 252 TFEU, it is the duty of the Advocate General, acting with complete impartiality and independence, to make, in open court, reasoned submissions on cases which, in accordance with the Statute of the Court of Justice of the European Union, require his or her involvement. The Court is not bound either by the Advocate General’s Opinion or by the reasoning on which it is based. Furthermore, neither the Statute of the Court of Justice of the European Union nor the Rules of Procedure make provision for the parties to submit observations in response to the Advocate General’s Opinion. Consequently, an interested party’s disagreement with the Opinion of the Advocate General cannot in itself constitute grounds justifying the reopening of the oral part of the procedure (judgment of 21 October 2021, Beeren‑, Wild-, Feinfrucht, C‑825/19, EU:C:2021:869, paragraphs 24 to 26 and the case-law cited).