83As regards the second head of material damage alleged, relating to a loss of opportunity, it is settled case-law that, in order to be established and give rise to compensation, the loss must be actual and definitive (see, to that effect, judgments of 21 February 2008, Commission v Girardot, C‑348/06 P, EU:C:2008:107, paragraphs 54 and 55; of 5 October 2004, Eagle and Others v Commission, T‑144/02, EU:T:2004:290, paragraph 165; and of 24 October 2018, Fernández González v Commission, T‑162/17 RENV, not published, EU:T:2018:711, paragraph 110).
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