87As regards the intensity of the review carried out by the Board of Appeal, it should be noted that, admittedly, in an action for annulment under Article 263 TFEU, the review carried out by the EU Courts is limited where it involves the assessment of highly complex scientific and technical facts. Regarding such assessments, the EU Courts are limited to reviewing whether they are vitiated by a manifest error, a misuse of powers or whether the author of the decision clearly exceeded the limits of its discretion (see judgment of 21 July 2011, Etimine, C‑15/10, EU:C:2011:504, paragraph 60 and the case-law cited).
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