115As is apparent from paragraphs 81 to 86 above, a decision requesting further information is adopted, in a context of uncertainty about the risks posed by the substance in question, on the basis of a draft prepared by the designated authority of a Member State. As was stated in paragraphs 70 to 76 above, the rules of Regulation No 1907/2006 on the procedure for adopting such an ECHA decision grants a significant role to the competent authorities of the Member States. They seek to involve Member State experts in the decision-making process, in order to make use of the available expertise at Member State level concerning the different scientific questions raised during the evaluation of a substance. Furthermore, as follows from the provisions at issue and from recital 67 of that regulation, the procedure laid down for substance and dossier evaluation is based on the principle that a unanimous agreement within the Member State Committee concerning draft decisions (or an agreement between the Member States and the ECHA) should provide the basis for an efficient system that respects the principle of subsidiarity. In that context, it is useful to note that, under Article 51(7) of that regulation, which is directly applicable to decisions taken for dossier evaluation and is applicable mutatis mutandis to decisions on substance evaluation under Article 52(2) of that regulation, in the absence of such an agreement, the decision on dossier or substance evaluation may not be adopted at ECHA level, but must be adopted by the Commission.