57In this connection, it should be recalled that, according to settled case-law, partial annulment of an act of the European Union is possible only if the elements which it is sought to have annulled can be severed from the remainder of the measure. That requirement of severability is not satisfied where the partial annulment of a measure would have the effect of altering its substance (Case C-224/03 France v Parliament and Council [2005] ECR I-4021, paragraphs 12 and 13, and Case C‑441/11 P Commission v Verhuizingen Coppens [2012] ECR, paragraph 38).
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