45It is also settled case-law that, under Article 44(1) in conjunction with Article 48(2) of the Rules of Procedure, the subject-matter of the claim must be defined in the application. A claim put forward for the first time in the reply modifies the original subject-matter of the application and must therefore be regarded as a new claim and be rejected as inadmissible (Case T-210/00 Biret et Cie v Council [2002] ECR II-47, paragraph 49, and the case-law cited there). The same reasoning applies where the initial subject-matter of the application is modified in observations on an objection of inadmissibility.
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