152Although they may not take a purely hypothetical approach to risk and may not base their decisions on a ‘zero-risk’ (see paragraph 145 above), the Community institutions must nevertheless take account of their obligation under the first subparagraph of Article 129(1) of the Treaty to ensure a high level of human health protection, which, to be compatible with that provision, does not necessarily have to be the highest that is technically possible (Case C-284/95Safety Hi-Tech [1998] ECR I-4301, paragraph 49).